Extract gel formula has inhibition zone in the range of 10.0 mm–10.3 mm, while nanoextract gel has inhibition zone in the range of 13.0 mm–13.4 mm. Extract gel formula had pH value in the range of 5.98–6.02, while nano extract gel had pH value in the range of 5.88–5.93. Extract gel formula had spreadability in the range of 51.75-53.35 mm, while nano extract gel has viscosity in the range of 65.125-72.75 mm. Extract gel formula had viscosity about 1540–1600 Ps, while nano extract gel had viscosity in the range of 487.63–501.01Ps. Gel evaluations showed that both formula (nanoparticle and extract gel formula) did not show any discoloration and still homogeny. Gel preparations were evaluated physically (organoleptic, homogeinity, spreadibility, and viscosity and rheology), chemically (pH value), and tested for their antimicrobial activity. Javanese turmeric extract and it's nanoparticles were then formulated in gel preparation. Javanese turmeric was extracted and then formulated into nanoparticles. This study aimed to compare antimicrobial activity difference between nanoparticle and extract gel. Acne vulgaris is one of skin’s disorder that caused by bacteria, the major cause is Propionibacterium acnes. Curcuminoid and xanthorrhizol contents are responsible for it's antimicrobial activity.
Javanese turmeric is one of the Indonesia’s authentic plant that has many benefits, antimicrobial effect is one of them.
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